50 Blessings is a mysterious underground organization in the Hotline Miami video game series. They are known for their violent and deadly missions, where operatives don animal masks to carry out assassinations and create chaos. The group operates in secrecy, with members receiving cryptic phone calls instructing them on their next target. 50 Blessings plays a central role in the game's narrative, as players navigate through a series of intense and bloody encounters while unraveling the organization's motives and connections to the larger story.

The enigmatic nature of 50 Blessings adds a layer of intrigue to the gameplay, as players must piece together clues and make moral decisions about their actions. The organization's influence is felt throughout the game world, with characters both fearing and idolizing its power. As players progress, they must confront the true nature of 50 Blessings and come to terms with the consequences of their allegiance to the group.